Scientific computing has become an integral part of modern science, enabling researchers to tackle complex problems and make new discoveries. HEP and RA are two scientific domains that rely heavily on scientific computing in the Edge/Cloud/HPC continuum, integrating high-performance computing, data analysis, Artificial Intelligence (AI) and data logistics, to achieve their research objectives. However, both domains face significant challenges in terms of computing capacity and capability, software co-design and refactoring, data management and logistics across the Edge-Cloud/HPC continuum, and workforce capacity and expertise. KER5 is a Technical Blueprint of a European compute and data continuum in the next decade, driven by the HEP and RA CoP and relevant to the broader scientific community that share similar challenges.